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对２－溴丙烷的生殖毒性研究，源于１９９５年韩国报道的一起２－溴丙烷职业卫生事故。２３名工人为事故受害者，其中８名男工中，２名罹患无精症，４名出现不同程度的精子减少［１－３］。这一事故报道立即引发了韩国、日本和中国职业卫生学家对２－溴丙烷男（雄）性生殖毒性?
The study of reproductive toxicity of 2-bromopropane originated from a 2-bromopropane occupational health accident reported in South Korea in 1995. Twenty-three workers were victims of the accident, of whom eight had azoospermia in eight men and four had varying degrees of sperm reduction [1-3]. The accident reported immediate male, male sexual toxicity of 2-bromopropane by Korean, Japanese and Chinese occupational hygienists.