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目的:研究入院时血小板与淋巴细胞比率(Platelet-to-Lymphocyte Ratio,PLR)对急性ST段抬高型心肌梗死(ST-segment elevation myocardia1 infarction,STEMI)患者冠脉介入治疗后无复流的预测价值。方法:共收集190例急性STEMI患者,发病12小时内并且行PCI(primary coronary intervention)术。按术中TIMI血流分级将病人分为2组:正常复流组(138例)和无复流组(52例),比较两组患者的基本临床资料、实验室检查结果及PCI结果,用Logistic回归分析无复流的预测因素,用受试者工作特征曲线(ROC曲线)论证得到PLR预测无复流的最佳临界值及其敏感度和特异度。结果:无复流组PLR显著高于正常复流组(246±98VS 169±108,P<0.01)。当PLR=188时,预测无复流的敏感度为70%,特异度为72%。结论:入院时PLR是急性STEMI患者PCI术后无复流的预测因素。
Objective: To study the prediction of no-reflow after percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction (STEMI) treated with Platelet-to-Lymphocyte Ratio (PLR) value. METHODS: A total of 190 acute STEMI patients were collected within 12 hours of onset and underwent primary coronary intervention (PCI). The patients were divided into two groups according to the TIMI flow classification: normal flow group (138 cases) and no-reflow group (52 cases). The basic clinical data, laboratory results and PCI results were compared between two groups Logistic regression analysis was used to predict the predictors of no-reflow. The receiver operating characteristic curve (ROC curve) was used to evaluate the predictive value of predicting no-reflow and its sensitivity and specificity. Results: PLR in no-reflow group was significantly higher than that in normal reflow group (246 ± 98VS 169 ± 108, P <0.01). At PLR = 188, the prediction of no-reflow sensitivity was 70% with a specificity of 72%. CONCLUSIONS: PLR at admission is a predictor of no-reflow after PCI in patients with acute STEMI.