小动脉阻塞性血栓在脑梗塞、心肌梗塞及糖尿病合并症等疾病发病中起着重要作用。D-二聚体(DD)是纤维蛋白降解后的特异性产物,升高表明体内血栓形成和溶解均增强。血小板功能直接影响血栓形成,而阿斯匹林可拮抗血小板功能。作者测定了一组血栓性疾病血清DD浓度,并观察阿斯匹林对其影响,旨在探讨阿斯匹林对血栓性疾病的治疗和预防的作用机理及应用价值。 1 材料与方法 脑梗塞病人90例,非胰岛素依赖性糖尿病病人28例,心肌梗塞病人11例,风心病伴心源性肝硬化 Arterial occlusive thrombus plays an important role in the pathogenesis of cerebral infarction, myocardial infarction and diabetic complications. D-dimer (DD) is a specific product of fibrin degradation, with an increase indicating increased thrombosis and lysis in vivo. Platelet function directly affects thrombus formation, whereas aspirin antagonizes platelet function. The authors measured the serum DD concentration of a group of thrombotic diseases and observed the effect of aspirin on it to explore the mechanism and value of aspirin’s treatment and prevention of thrombotic diseases. 1 Materials and Methods 90 patients with cerebral infarction, non-insulin-dependent diabetes 28 patients, 11 patients with myocardial infarction, rheumatic heart disease with cardiac cirrhosis