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目的探讨老年钙化性主动脉瓣狭窄(senile calcific aortic stenosis,SCAS)与冠心病的关系。方法收集沈阳军区总医院收治的SCAS患者173例。所有患者均行常规检查与冠状动脉造影检查,明确冠脉病变并行Gensini评分,进行相关统计分析。结果将所有患者按跨主动脉瓣平均压差分为轻、中、重3组。经冠脉造影检查明确29例并发冠心病,冠心病阳性率在动脉粥样硬化(AS)重度狭窄组为25%>AS中度狭窄组(16%)>AS轻度狭窄组(8%)。3组间冠心病阳性率存在显著差异(P<0.05),具有统计学意义。此外,3组平均Gensini评分分别为0.906、1.430和5.905,随着主动脉瓣狭窄程度的增加,评分也具有增加趋势,表明二者具有相关性。结论 SCAS与冠心病间存在相关性。
Objective To investigate the relationship between senile calcific aortic stenosis (SCAS) and coronary heart disease. Methods A total of 173 patients with SCAS admitted to Shenyang Military Region General Hospital were collected. All patients underwent routine examination and coronary angiography, coronary artery lesions were identified with Gensini score, the relevant statistical analysis. Results All patients were divided into mild, moderate and severe groups according to the mean trans-aortic valve pressure difference. Coronary angiography confirmed that 29 cases were complicated by coronary heart disease. The positive rate of coronary heart disease was 25% in AS severe stenosis group, 16% in AS moderate stenosis group and 8% in AS mild stenosis group. . The positive rate of coronary heart disease in the three groups was significantly different (P <0.05), with statistical significance. In addition, the mean Gensini scores of the three groups were 0.906, 1.430 and 5.905, respectively. As the degree of aortic stenosis increased, the score also had an increasing trend, indicating that the two were related. Conclusion There is a correlation between SCAS and coronary heart disease.