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【目的】探讨认知行为干预（Cognitive behavioral therapy ，CBT ）对干眼症患者焦虑抑郁情绪的影响。【方法】将90例干眼症患者按随机数字表法分为观察组和对照组，每组45例，对照组进行眼科常规护理，观察组在常规护理的基础上给予CBT ，采用zung氏焦虑自评量表（SAS ）与抑郁自评量表（SDS ）对两组患者出入院时的焦虑和抑郁情绪进行评价，对两组患者护理满意度、疗效进行比较。【结果】观察组患者出院时SAS评分为（40．25±8．14）分明显低于对照组（45．21±8．05）分；SDS评分为（39．95±8．07）分，也明显低于对照组SDS评分（44．68±8．28）分，两组评分比较差异均有统计学意义（ tsas＝3．17，P＜0．01，tsds ＝2．52，P＜0．05）；观察组患者对护理的总满意度高于对照组，差异有显著意义（100％ v s 73．33％，χ2＝13．85， P ＜0．01）；观察组有效率也高于对照组，差异有显著意义（93．33％ v s 77．78％，χ2＝4．41， P ＜0．05）。【结论】CBT能降低干眼症患者焦虑和抑郁情绪，规范健康认知和行为，改善患者预后，提高患者生活质量，方法简单，值得推广。“,”[Objective] To explore the effects of cognitive behavior intervention on anxiety and depression of patients with dry eye emotions .[Methods]A total of 90 patients were randomly divided into intervention and control groups (n=45 each) .The control group was subject to routine care while the intervention group received cognitive behavioral intervention on the basis of routine care .And two groups were compared with re‐gards to anxiety ,depression ,satisfaction and efficacy .[Results] The self‐rating anxiety scale (SAS) score was 40 .25 ± 8 .14 in intervention group versus 45 .21 ± 8 .05 in control group .And the self‐rating depression scale (SDS) score was 39 .95 ± 8 .07 in intervention group versus 44 .68 ± 8 .28 in control group .And the differences were statistically significant ( P <0 .05) .The overall satisfaction rate was 100% in intervention group versus 73 .33% in control group .And the difference was significant ( P<0 .01) .The effective rate was 93 .33% in intervention group versus 77 .78% in control group .And the difference was significant ( P <0 .05) .[Conclusion] Cognitive behavioral intervention can reduce anxiety and depression ,enhance cognitive and behavioral health ,improve the prognosis and quality‐of‐life of patients with dry eye emotions .