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目的观察异丙托溴铵溶液(爱全乐)和布地奈德气雾剂联合治疗毛细支气管炎的临床疗效。方法 74例毛细支气管炎患儿随机分为两组,对照组39例,治疗组35例,两组均给予抗感染、解痉止咳、对症支持等治疗,治疗组加用吸入用异丙托溴铵溶液250μg、布地奈德气雾剂0.5mg,加入生理盐水2ml中雾化吸入,2次/d,治疗5~7d。结果治疗组咳嗽气喘、肺部干罗音消失时间及平均治疗天数较对照组明显缩短,差异有统计学意义(P<0.05),而未见明显的不良反应。结论应用异丙托溴铵溶液和布地奈德气雾剂联合治疗毛细支气管炎临床疗效确切、安全可靠,值得临床推广运用。
Objective To observe the clinical efficacy of ipratropium bromide solution (Aimengle) and budesonide aerosol in the treatment of bronchiolitis. Methods A total of 74 children with bronchiolitis were randomly divided into two groups: control group (39 cases) and treatment group (35 cases). Both groups were given anti-infective, antispasmodic, cough and symptomatic treatment. Patients in treatment group were treated with ipratropium 250μg of ammonium solution and budesonide aerosol 0.5mg, adding 2ml of normal saline inhalation, 2 times / d, the treatment of 5 ~ 7d. Results The cough and asthma in the treatment group, the disappearance time of the dry rales in the lung and the average treatment days were significantly shorter than those in the control group (P <0.05), but no obvious adverse reactions were observed. Conclusion The combination of ipratropium bromide solution and budesonide aerosol in the treatment of bronchiolitis is effective, safe and reliable, and is worthy of clinical application.