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615小鼠经H615瘤块移植致敏后并不能抵御相同肿瘤的接种攻击,亦无存活时间延长的现象。用H615组织匀浆免疫的小鼠接种肿瘤后,肿瘤生长加速;60天处死时平均肿瘤重量较对照组明显增加(P<0.05),发癌率也由对照组的80%增至100%(P>0.05)。但同时接受上述处理的小鼠却没有明显的肿瘤促进作用,文内对此进行了讨论。 实验结果显示主动免疫不能抑制肿瘤的生长,反而有促进肿瘤生长的可能。
The sensitization of 615 mice after H615 tumor mass transplantation could not resist the challenge of the same tumor and there was no prolongation of survival time. After inoculation of tumors with H615 tissue-immunized mice, tumor growth accelerated; the average tumor weight at 60 days of sacrifice was significantly higher than that of the control group (P<0.05), and the cancer-generating rate was also increased from 80% to 100% in the control group ( P>0.05). However, the mice that received the above treatment did not have obvious tumor-promoting effect, which was discussed in the article. The experimental results show that active immunity can not inhibit the growth of tumors, but instead promote the growth of tumors.