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This work aimed to study UV-resistant strains of Pseudomonas aeruginosa,to propose a formulation of the kinetics of secondary treated wastewater disinfection and to underline the influence of suspended solids on the inactivation kinetics of these strains.Some investigations were carried out for the validation of some simulation models,from the simplest,the kinetics model of Chick-Watson reduced to first order,to rather complex models such as multi-kinetic and Collins-Selleck models.Results revealed that the involved processes of UV irradiation were too complex to be approached by a simplified formulation,even in the case of specific strains of microorganisms and the use of nearly constant UV radiation intensity.In fact,the application of Chick-Watson model in its original form is not representative of the kinetics of UV disinfection.Modification,taking into account the speed change during the disinfection process,has not significantly improved results.On the other hand,the application of Collins-Selleck model demonstrates that it was necessary to exceed a least dose of critical radiation to start the process of inactivation.To better explain the process of inactivation,we have assumed that the action of disinfectant on the survival of lonely microorganisms is faster than its action on suspended solids protected or agglomerated to each others.We can assume in this case the existence of two inactivation kinetics during the processes(parallel and independent)of the first-order.For this reason,the application of a new kinetic model by introducing a third factor reflecting the influence of suspended solids in water on disinfection kinetics appeared to be determinant for modeling UV inactivation of P.aeruginosa in secondary treated wastewater.