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目的:调查糖尿病(DM)足感染与抗菌用药的特点。方法:对60例DM足患者的感染病原菌,抗菌用药等进行分析。结果:81.67%(49例)患者应用抗菌药物10类28个品种,前3位品种为头孢哌酮/舒巴坦,甲硝唑及头孢曲松。细菌培养阳性率63.64%,治癒37例,好转23例。结论:DM足感染多为混合性细菌感染,患者以高龄为主,多脏器(尤其以肾脏)受累,应采用杀菌性抗菌药为主的联合用药,并制订个体化给药方案。
Objective: To investigate the characteristics of diabetic foot infections and antibacterial drugs. Methods: Sixty patients with DM foot infected with pathogens, antimicrobial medication were analyzed. Results: In 81.67% (49 cases), 28 kinds of antibacterial drugs were applied in 10 categories and the top three varieties were cefoperazone / sulbactam, metronidazole and ceftriaxone. The positive rate of bacterial culture was 63.64%, 37 cases were cured and 23 cases improved. CONCLUSIONS: Most of the DM foot infections are mixed bacterial infections. The patients are mainly elderly persons. Multiple organs (especially the kidneys) are involved. Bactericidal antibacterial drugs should be used as the main combination and individualized drug delivery plans should be formulated.