除虫菊酯及其类似物作为谷物的防护剂和毒理机制

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除虫菊酯类似物这一类杀虫药剂是近十几年来发展得最迅速的一类杀虫药剂。这是因为它有许多优点,缺点较少,是比较理想的一类杀虫药剂。近十几年来,发现许多杀虫药剂具有公害的问题,而另一些种类对人畜的毒性还过高,虽然污染较不严重。而除虫菊酯类却对人畜是十分安全的,它们能极快地在体内降解,没有急性中毒和慢性中毒问题。在环境中,一般也都极快降解(有几种,如二氯苯醚菊酯、溴氰菊酯等)持久期较长,但或是毒性不高,或是用量极少,也没有污染中毒的危险,它们也没有致癌、致畸及诱变问题,在残留的极微量作用下,也不产生任何不利的生理生化细微效应。除虫菊酯类似物中多数对鱼、鸟的毒性也不高。除虫菊酯及其类似物都是广谱性杀虫药剂,这是它的一个优点,也是一个缺点。一方面它对于多种昆虫都能防治,因此在农业上(1973年以后,二氯苯醚菊酯出现才开始应用),林业上,卫生害虫,仓库害虫、家庭害虫等等方面均可应用,它们的另一些优点是,化合物没有刺激性、不引起燃 Pyrethrins Analogues This class of insecticide is the most rapidly developing class of insecticide in nearly a decade. This is because it has many advantages, disadvantages less, is a more ideal class of insecticide. In the past decade or so, many insecticides have been found to have the problem of pollution, while others have been found to be too toxic to humans and animals, albeit less polluting. Pyrethroids, on the other hand, are very safe for humans and animals. They can degrade rapidly in the body without the problems of acute poisoning and chronic poisoning. In the environment, it is also generally very fast degradation (there are several, such as permethrin, deltamethrin, etc.) longer duration, but or not toxic, or the amount of very little, no pollution They also have no carcinogenic, teratogenic and mutagenic problems, and do not produce any adverse physiological and biochemical subtle effects under the minimal residual effect. Pyrethrins most of the fish, birds are not very toxic. Pyrethrins and their analogs are broad-spectrum insecticides, which is one of its advantages, but also a disadvantage. On the one hand, it can prevent and control many kinds of insects, so it can be used in agriculture (since the appearance of permethrin after 1973), forestry, sanitary pests, storage pests, family pests and so on, Some of their other advantages are that the compounds are not irritating and do not cause burning
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