目的:评价非顺应球囊后扩张对药物洗脱支架(DES)植入后支架内亚急性血栓的影响。方法:2006年1月~2008年9月住院并植入DES共305例,根据是否采用非顺应球囊后扩张分为非后扩张组及后扩张组,记录所有患者的临床特征、冠脉病变情况、DES植入情况及亚急性血栓形成情况,观察并分析非顺应性球囊后扩张患者发生亚急性血栓形成的情况。结果:两组患者的临床特征、冠脉病变情况、支架植入数量及平均长度均无统计学差异。非后扩张组及后扩张组支架内亚急性血栓发生率分别为1.2%和0%,没有统计学差异。结论:非顺应性球囊后扩张不能显著降低DES植入后亚急性血栓发生率。 PURPOSE: To evaluate the effect of non-compliant post-balloon dilatation on sub-acute stent thrombosis after drug-eluting stent (DES) implantation. Methods: From January 2006 to September 2008, 305 patients were enrolled into hospital and DES were enrolled. According to whether non-adaptive balloon dilatation was divided into non-dilatation group and post-dilatation group, the clinical features, coronary artery disease Situation, DES implantation and subacute thrombosis, observation and analysis of non-compliance balloon dilatation in patients with subacute thrombosis. Results: There was no significant difference in clinical features, coronary lesions, number of stent implantation and mean length between the two groups. The rates of subacute thrombosis in non-post-dilation and post-dilatation stents were 1.2% and 0%, respectively, with no significant difference. CONCLUSIONS: Non-compliant balloon dilatation does not significantly reduce the incidence of subacute thrombosis after DES implantation.