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鉴于人绒毛膜促性腺激素 (ｈＣＧ)疫苗研究的现状和现代疫苗发展的趋势 ,我们提出了研制ｈＣＧ嵌合肽免疫原的生物工程路线 ,其优点是可以任意组合多种广谱Ｔ细胞表位 (ＴＣＥ)和靶抗原的三个线性Ｂ细胞表位 (ＢＣＥ) ,从而在无需特殊佐剂的情况下达到抗体生成水平高、中和性及
Given the current status of human chorionic gonadotropin (hCG) vaccine research and the trend toward the development of modern vaccines, we propose a bioengineered route for the development of hCG chimeric peptide immunogens with the advantage of combining any of a broad spectrum of T cell epitopes (TCE) and three linear B cell epitopes (BCEs) of target antigens to achieve high levels of antibody production, neutralization and