论文部分内容阅读
目的:观察督灸联合阿仑膦酸钠肠溶片治疗绝经后骨质疏松症(脾肾阳虚证)的临床疗效。方法:选取92例绝经后骨质疏松症患者,随机分为对照组和治疗组各46例。对照组予钙尔奇D 600合阿仑膦酸钠肠溶片治疗,治疗组在对照组基础上予督灸治疗。观察两组治疗后肝肾功能、血清骨钙素(BGP)、血清钙(Ca)及腰椎2-4(L2-4)、股骨粗隆和Ward三角的骨密度。结果:治疗后SCr治疗组低于对照组(P<0.05);两组治疗后血清Ca2+、BGP与组内治疗前比较,差异均有统计学意义(P<0.05);治疗后血清Ca2+治疗组高于对照组(P<0.05),血清BGP低于对照组(P<0.05);两组治疗后L2-4、股骨粗隆、Ward三角骨密度与组内治疗前比较,差异均有统计学意义(P<0.05);治疗后L2-4、股骨粗隆、Ward三角骨密度治疗组均高于对照组(P<0.05);对照组总有效率为82.6%,治疗组总有效率为95.7%,治疗组优于对照组(P<0.05)。结论:督灸联合阿仑膦酸钠肠溶片治疗绝经后骨质疏松症(脾肾阳虚证)有较好疗效。
Objective: To observe the clinical efficacy of Governor moxibustion combined with alendronate sodium enteric-coated tablets in the treatment of postmenopausal osteoporosis (spleen and kidney yang deficiency syndrome). Methods: 92 cases of postmenopausal osteoporosis were randomly divided into control group and treatment group of 46 cases. The control group was treated with Gal-600 and alendronate enteric-coated tablets, and the treatment group was given supervised moxibustion treatment on the basis of the control group. The liver and kidney function, bone BGP, serum Ca (Ca2 +) and lumbar 2-4 (L2-4), femoral trochanter and Ward triangle were observed after treatment. Results: After treatment, SCr treatment group was lower than the control group (P <0.05); serum Ca2 +, BGP levels after treatment in both groups were significantly different (P <0.05); after treatment, serum Ca2 + treatment group (P <0.05), serum BGP was lower than that of the control group (P <0.05). The difference of L2-4, trochanter and Ward triangle BMD between two groups after treatment was statistically significant (P <0.05). After treatment, L2-4, femur trochanter and Ward triangle bone mineral density in the treatment group were higher than those in the control group (P <0.05). The total effective rate in the control group was 82.6%, and the total effective rate in the treatment group was 95.7 %, The treatment group is better than the control group (P <0.05). Conclusion: Governor moxibustion combined alendronate sodium enteric-coated tablets for the treatment of postmenopausal osteoporosis (spleen and kidney yang deficiency syndrome) has a good effect.