Traditional uses,phytochemistry and pharmacology of Clerodendron glandulosum Coleb - a review

来源 :Asian Pacific Journal of Tropical Medicine | 被引量 : 0次 | 上传用户:zylgg
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Present review for the first time provides a complete botanical description and information on ethnomcdicinal uses of Clerodendron glandulosum.Coleb(CG:Fam.Verbenaceae).Recent studies conducted from our laborator) provide pharmacological evidence for its anti-hypertensive,antidiabetic and anti-obesity potentials.Further,its beneficial potential in preventing in vitro and in vivo non-alcoholic steatohepatitis and atherosclerosis and potent hcpatoprotective and free radical scavenging abilities along with its acute and sub- chronic toxicologiesl evaluations are also reported from our laboratory.In keeping with its traditional uses,CG extract was capable of ameliorating experimentally induced hypertension,diabetes and obesity.Its beneficial potential against NASH induced oxidative stress and atherosclerosis can be attributed to its potent free radical scavenging potential.Non—toxic nature of CG leaf extract further provides added merit to its reported pharmacological properties.The present review summarizes the pioneering scientific evidence for the pharmacological effects of CG against related metabolic disorders like hypertension,diabetes and obesity along with anti oxidant potential and beneficial elicits against non alcoholic steatohepatitis. Present review for the first time provides a complete botanical description and information on ethnomcdicinal uses of Clerodendron glandulosum. Coleb (CG: Fam. Verbenaceae). Review studies conducted from our laborator) provide pharmacological evidence for its anti-hypertensive, antidiabetic and anti-obesity potentials. Future, its beneficial potential in preventing in vitro and in vivo non-alcoholic steatohepatitis and atherosclerosis and potent hcpatoprotective and free radical scavenging abilities along with its acute and sub- chronic toxicologies, evaluations are also reported from our laboratory. keeping with its traditional uses, CG extract was capable of ameliorating experimentally induced hypertension, diabetes and obesity. Its beneficial potential against NASH induced oxidative stress and atherosclerosis can be attributed to its potent free radical scavenging potential. Non-toxic nature of CG leaf extract and added merit to its reported pharmacological properties.The pres ent review summarizes the pioneering scientific evidence for the pharmacological effects of CG against related metabolic disorders like hypertension, diabetes and obesity along with anti oxidant potential and beneficial elicits against non alcoholic steatohepatitis.
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