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目的:评价头孢曲松钠与炎琥宁注射液联用治疗急性感染性心内膜炎患者的临床疗效和安全性。方法:选取2013年1月—2014年2月间就诊并接收治疗的急性感染性心内膜炎患者84例患者为研究对象,结合患者入院时间的先后将其分为观察组(42例)和对照组(42例);观察组患者均给予头孢曲松钠与炎琥宁注射液联用治疗,对照组患者则给予单用头孢曲松钠治疗,比较两组患者治疗后的总有效率和不良反应的发生率。结果:观察组患者治疗后的总有效率为90.48%优于对照组为76.19%(P<0.05);不良反应的发生率为4.76%低于对照组患者为7.14%(P<0.05)。结论:头孢曲松钠与炎琥宁注射液联用治疗急性感染性心内膜炎患者的疗效优于单用头孢曲松钠的治疗,且疗效好、安全性高。
Objective: To evaluate the clinical efficacy and safety of ceftriaxone sodium combined with Yanhuning injection in the treatment of patients with acute infectious endocarditis. Methods: A total of 84 patients with acute infective endocarditis admitted to our hospital from January 2013 to February 2014 were enrolled in the study. Patients were divided into observation group (n = 42) and admission group The control group (n = 42). The patients in the observation group were treated with ceftriaxone sodium and Yanhuning injection. The patients in the control group were treated with ceftriaxone sodium alone. The total effective rate The incidence of adverse reactions. Results: The total effective rate of observation group was 90.48% after treatment, which was 76.19% (P <0.05) better than that of control group. The incidence of adverse reactions was 4.76%, which was lower than that of control group (7.14%, P <0.05). Conclusion: The efficacy of ceftriaxone sodium and Yanhuning injection in the treatment of patients with acute infectious endocarditis is better than that of ceftriaxone sodium alone. The curative effect is good and the safety is high.