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目的分析表皮样囊肿术后颅内出血的特点及其相关因素。方法对428例表皮样囊肿患者的临床资料进行回顾性分析,采用单因素分析及Logistic多元回归,筛选出与术后出血相关性较大的因素。结果43例(10.05%)出现术后颅内出血,其中术后5d及5d以后出现颅内出血者占总体出血者的69.77%。出血组与未出血组年龄及肿瘤直径均无显著性差异,在肿瘤部位、脑挫伤、术后脑膜炎方面有显著性差异(P值分别为0.002、0.008、0.018)。Logistic回归分析结果显示,脑挫伤(P=0.004,OR=7.07)、术后脑膜炎(P=0.016,OR=2.27)与术后出血的关系更密切。结论表皮样囊肿术后颅内出血发生率高,并且术后1周左右的迟发性出血比例较大。肿瘤部位、脑挫伤、术后脑膜炎3个因素与术后出血关系较为密切,尤其是后两者。
Objective To analyze the characteristics and related factors of intracranial hemorrhage after epidermoid cyst. Methods The clinical data of 428 patients with epidermoid cyst were retrospectively analyzed. Univariate analysis and logistic multiple regression analysis were used to screen out the factors that had a significant correlation with postoperative bleeding. Results Postoperative intracranial hemorrhage occurred in 43 cases (10.05%), of which 69.77% of the total hemorrhage occurred after 5 days and 5 days after operation. There was no significant difference in the age and tumor diameter between the hemorrhage group and the non-hemorrhage group. There were significant differences in the tumor site, brain contusion and postoperative meningitis (P = 0.002, 0.008, 0.018 respectively). Logistic regression analysis showed that brain contusion (P = 0.004, OR = 7.07) and postoperative meningitis (P = 0.016, OR = 2.27) were more closely related to postoperative bleeding. Conclusion The incidence of intracranial hemorrhage after epidermoid cyst is high, and the rate of delayed hemorrhage after 1 week is higher. Tumor site, brain contusion, postoperative meningitis three factors and postoperative bleeding is more closely related, especially after the two.