近年来,对肝细胞癌的诊断已随着影像诊断的发展而有很大的提高。与此同时,作为肿瘤标记的AFP也在临床上起到很大的作用。但在慢性肝炎和肝硬化等AFP亦可阳性,这便与AFP浓度较低的肝细胞癌不易鉴别。据日本肝癌研究会报告,AFP在400ng/ml以上的肝细胞癌病例不过44.5％,因而有必要研究特 In recent years, the diagnosis of hepatocellular carcinoma has greatly improved with the development of imaging diagnosis. At the same time, AFP as a tumor marker also plays a large role in clinical practice. However, AFP may also be positive in chronic hepatitis and cirrhosis, which is not easily distinguished from hepatocellular carcinoma with low AFP concentration. According to the report of the Japanese Society for the Study of Liver Cancer, the number of cases of hepatocellular carcinoma with AFP above 400ng/ml is only 44.5%, so it is necessary to study