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目的了解广水辖区内高中生麻疹、脊髓灰质炎(简称脊灰)、流行性乙型脑炎(简称乙脑)免疫效果抗体水平,为全市制定免疫防控策略提供科学依据。方法对全市所辖3所高中16~18岁组的8 504名高中生,采用酶联免疫吸附试验进行麻疹、脊灰及乙脑Ig G抗体检测。结果广水市16~18岁组的健康高中生麻疹抗体、脊灰抗体、乙脑抗体阳性率分别为92.2%、88.4%、86.1%。3种抗体保护水平均达到了85%以上;不同年龄组麻疹抗体阳性率差异有统计学意义(χ2=17.52,P<0.05)、脊灰抗体阳性率差异有统计学意义(χ2=17.52,P<0.05),不同年龄组乙脑抗体阳性率差异无统计学意义(χ2=1.11,P>0.05);不同性别的麻疹抗体阳性率差异无统计学意义(χ2=0.85,P>0.05)、脊灰抗体阳性率差异无统计学意义(χ2=0.529,P>0.05)、乙型脑炎抗体阳性率差异无统计学意义(χ2=0.397,P>0.05)。结论广水市16~18岁组健康高中生麻疹、脊灰、乙脑抗体阳性率达到抵御相应疾病的水平,但脊灰、乙脑抗体阳性率有待提高,应继续加强监测工作,根据监测结果进行应急补种工作。
Objective To understand the immune effect of measles, poliomyelitis (referred to as polio) and epidemic encephalitis (JE) in high school students in Guangshui area to provide a scientific basis for the city to formulate immunization prevention and control strategies. Methods 8 504 high school students from 16 to 18 years old in 3 high schools under the jurisdiction of the city were tested for Ig G antibody against measles, poliomyelitis and Japanese encephalitis using enzyme-linked immunosorbent assay (ELISA). Results The positive rates of measles antibody, polio antibody and encephalitis antibody in healthy high school students aged from 16 to 18 in Guangshui were 92.2%, 88.4% and 86.1% respectively. The antibody level of three kinds of antibodies reached more than 85%. The positive rate of measles antibody in different age groups was significantly different (χ2 = 17.52, P <0.05), the positive rate of poliovirus antibody was significant difference (χ2 = 17.52, P (Χ2 = 1.11, P> 0.05). There was no significant difference in the positive rates of measles antibody between different sexes (χ2 = 0.85, P> 0.05) There was no significant difference in the positive rate of gray antibody (χ2 = 0.529, P> 0.05). There was no significant difference in the positive rate of antibody against Japanese encephalitis (χ2 = 0.397, P> 0.05). Conclusion The positive rates of measles, poliovirus and Japanese encephalitis in healthy high school students in Guangshui City reach the level of resistance to the corresponding diseases in 16-16 age group. However, the positive rate of poliovirus and JE antibody needs to be improved. Monitoring work should continue to be strengthened. According to the monitoring results Emergency replanting work.