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目的分析2005-2008年云南省伤寒、副伤寒高发地区——玉溪市红塔区的甲型副伤寒流行趋势,探讨其流行特征和影响因素。方法采用描述流行病学方法,对云南省玉溪市红塔区2005-2008年伤寒、副伤寒病例资料进行统计分析,并与云南省和玉溪市伤寒、副伤寒发病情况进行比较分析。结果云南省玉溪市红塔区城区发病率(374.59/10万)显著高于农村(96.51/10万);发病高峰呈双峰,持续时间较长。<15岁小年龄段发病率及构成均分别低于云南省、玉溪市;农民、散居和幼托儿童比例较低,而大中专学生、工人和干部职员等人群构成较高。2008年红塔区实验室确诊病例全部为甲型副伤寒病例,其分子分型(PFGE)检测结果主要集中在3种带型,表明传染来源具有较高同源性。结论红塔区甲型副伤寒占绝对优势,当地伤寒、副伤寒的流行特征与云南省和玉溪市有明显差异,应根据红塔区伤寒、副伤寒流行病学特征和可能的危险因素制定有针对性的干预策略。
Objective To analyze the epidemic tendency of Paratyphoid A in Hongta District of typhoid fever and paratyphoid fever in Yunnan Province during 2005-2008, and to discuss its epidemiological characteristics and influencing factors. Methods Descriptive epidemiological methods were used to analyze the data of cases of typhoid fever and paratyphoid fever in Hongta District, Yuxi City, Yunnan Province from 2005 to 2008, and compared with the incidence of typhoid and paratyphoid fever in Yunnan and Yuxi. Results The incidence rate (374.59 / 100,000) in Hongta district of Yuxi city in Yunnan province was significantly higher than that in rural areas (96.51 / 100,000). The peak incidence was bimodal and lasted for a long time. The prevalence and composition of children younger than 15 years old were lower than that of Yuxi City, Yunnan Province respectively. The proportion of peasants, diasporas and child care children was low while that of college students, workers, cadres and staff was relatively high. All the confirmed cases in Hongta District Laboratory in 2008 were all Paratyphorosis A cases. The results of PFGE test mainly focused on three types of belts, indicating that the source of infection has high homology. Conclusions Paragonimmunopsin A in Hongta District has absolute advantage. The prevalence of typhoid fever and paratyphoid fever in Hongta District is obviously different from that in Yunnan Province and Yuxi City. According to the epidemiological characteristics of typhoid and paratyphoid fever in Hongta District and possible risk factors, Intervention strategy.