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目的探讨口服米非司酮配伍阴道后穹窿放置米索前列醇用于中晚期妊娠引产的有效性。方法将120例中晚期妊娠引产者随机分为观察组60例(米非司酮联合米索前列醇)和对照组60例(利凡诺)。对两组的引产效果进行比较。结果 A组引产成功60例,B组引产成功为48例。A组从用药至出现规律宫缩时间、规律宫缩至胎儿娩出时间均明显短于B组(P<0.05)。结论口服米非司酮配伍阴道后穹窿放置米索前列醇用于中晚期妊娠引产,具有成功率高,产程短、疼痛轻等优势,在临床中值得推广。
Objective To investigate the effectiveness of oral mifepristone in combination with vaginal posterior fornix in misoprostol for induction of labor in late pregnancy. Methods 120 cases of late pregnancy induced abortion were randomly divided into observation group of 60 cases (mifepristone combined with misoprostol) and 60 cases of control group (rivanol). The effects of induction of labor in both groups were compared. Results A group of 60 cases successful induction of labor, B group 48 cases of successful induction. A group from the medication to the occurrence of regular contractions time, regular contractions to the time of fetal delivery were significantly shorter than the B group (P <0.05). Conclusion Oral mifepristone with vaginal posterior fornix placed misoprostol for induction of labor in late pregnancy, with high success rate, short delivery, pain and other advantages, worth promoting in the clinic.