例4 男性,32岁,农民。全身皮肤扁平样疣赘28年。面、颈、躯干、四肢(尤其是肢端)有密集扁平疣样疣赘,互相融合,呈斑块状(封三图7)。组织病理学:表皮角化过度,棘层和颗粒层增厚,表皮突延长。棘细胞层上部及颗粒层有许多空泡化细胞(现称挖空细胞)。空泡化细胞有呈团块状倾向。真皮内无改变(封三图8)。诊断:根据自幼发病,全身皮肤有扁平疣样损害,组织病理学也为扁平疣样改变,诊断为疣状表 Example 4 male, 32 years old, farmer. Flat skin warts 28 years. Face, neck, trunk, limbs (especially the extremities) have dense flat wart-like warts, merged with each other, was plaque (cover three Figure 7). Histopathology: epidermal hyperkeratosis, stratum spinosum and granular layer thickening, epidermal protrusion. The top of the spinous cell layer and the granular layer has many vacuolar cells (now called hollow cells). The vacuolization cells have a tendency of clumps. No change in the dermis (seal three Figure 8). Diagnosis: According to the onset of childhood, the whole body has flat wart-like skin lesions, histopathology is also flat wart-like changes, the diagnosis of verrucous