噻甲羧肟头孢菌素(ceftazidime)是一第三代头孢菌素,除抗菌谱广外,对绿脓杆菌的作用非常显著,且在成人未发现毒性.本文报道本药在早产儿的药代动力学和安全性研究,并确定给药剂量.41名两周内的新生儿,静注(iv)或肌注(im)本药25mg/kg,一天二次,在给药前后 Ceftazidime is a third-generation cephalosporin, in addition to antibacterial spectrum, the role of Pseudomonas aeruginosa is very significant, and no toxicity found in adults.This article reports the drug in preterm children’s medicine The pharmacokinetic and safety studies were performed and the dose was determined.41 newborns within two weeks were injected intravenously (iv) or intramuscularly with 25 mg / kg of the drug, twice a day, before and after administration