药源性消化系统疾病系指在治疗或诊断用药过程中,因药物的毒副作用或药物相互作用而引起的消化系统疾病。一、粘膜炎症: 1.抗肿瘤药物氟脲嘧啶、甲氨喋呤、环磷酰胺、长春新碱,以及四环素、放疗药物等,能抑制细胞增殖,影响消化道粘膜上皮的修复,从而引起口炎、咽炎、食道炎及肠炎等临床症状。2.内服阿司匹林类药物、碘制剂及氯化铵等,可直接刺激胃粘膜而引起胃炎。 Drug-induced digestive system disease refers to the digestive system diseases caused by drug side effects or drug interactions in the course of treatment or diagnosis. First, the mucosal inflammation: 1. Antitumor drugs fluorouracil, methotrexate, cyclophosphamide, vincristine, and tetracycline, radiotherapy drugs, can inhibit cell proliferation, affecting the repair of gastrointestinal mucosal epithelium, causing the mouth Inflammation, pharyngitis, esophagitis and enteritis and other clinical symptoms. 2. Oral aspirin drugs, iodine and ammonium chloride, etc., can directly stimulate the gastric mucosa and cause gastritis.