应用扫描电镜观察了吡喹酮对体外培养的不同发育期血吸虫皮层的损害。结果表明,吡喹酮对虫龄为3～14天童虫的体表皮层无或仅有轻度损害,而虫龄为3h及21～42天的童虫或成虫的皮层则可受到中度或严重的损害。这与小鼠于感染后不同时期口服吡喹酮,自其体内取虫观察的结果相仿。本文就吡喹酮对不同发育期血吸虫皮层损害的意义进行了简要的讨论。 Scanning electron microscopy was used to observe the damage of praziquantel to schistosome cortex in different developmental stages. The results showed that psoraquin did not or only mildly damaged the body surface cortex of 3 ~ 14 days old worms, while the caterpillars of adult worms or adult worms 3h and 21 ~ 42 days could be moderately or Serious damage. This oral administration of praziquantel at different times after infection in mice, the results obtained from the body to take the worm observation. This article briefly discussed the significance of praziquantel for the different stages of schistosome cortical damage.