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目的：探讨不同栽培居群板蓝根抗内毒素活性差异形成的原因。方法：采集了板蓝根药材１９份，将１２份种子在上海进行了异地栽培，又将四倍体种子栽培于５个有代表性的产地，通过抗内毒素实验对药材样品进行比较。结果：采集的１９份样品活性差异十分明显，异地栽培后的１２份样品差异并未消失，四倍体板蓝根在５个产地栽培后活性基本持平。结论：在影响板蓝根抗内毒素活性的诸多因素中，种质是首要的，环境相对次之。
Objective: To explore the reasons for the different anti-endotoxin activities of Banlangen from different cultivated populations. Methods: Nineteen parts of Radix Isatidis were collected, 12 seeds were cultivated in different places in Shanghai, and tetraploid seeds were cultivated in five representative producing areas. The medicinal samples were compared by anti-endotoxin test. Results: The differences of the activity of 19 samples collected were obvious. The difference of 12 samples did not disappear after cultivated in different places. The activity of the tetraploids of Isatis indigotica was basically the same after the cultivation in 5 producing areas. Conclusion: Among the many factors that affect the anti-endotoxin activity of Radix isatidis, germplasm is the most important and the environment is relatively secondary.