论文部分内容阅读
生物科学和技术的新进展,特别是有关预防接种方面的进展,现已为减少由人类病原性微生物所致疾病的发病和死亡人数提供了可能性。但每年约有五百万婴儿死于可用现有疫苗预防的疾病。有些疾病由于经济或其他原因尚无疫苗,估计每年约有2亿人感染乙型肝炎病毒,1亿5千万人感染疟疾。艾滋病的迅速传播迫切需要疫苗加以控制。最近在病毒疫苗方面所取得的进展表明,不经感染即可用非感染性疫苗建立有效而持久的免疫。这些进展包括DNA重组技术的应用、多肽合成、内影象(独特型)抗体以及在
Recent advances in biological sciences and technology, and in particular on vaccination, now offer the possibility of reducing the incidence and deaths of diseases caused by human pathogenic microorganisms. However, about 5 million babies die each year from diseases that can be prevented with existing vaccines. Some diseases have no vaccine for economic or other reasons. An estimated 200 million people are infected with the hepatitis B virus each year and 150 million people are infected with malaria. The rapid spread of AIDS is in urgent need of vaccine control. Recent advances in viral vaccines have demonstrated that effective and long-lasting immunity can be established with non-infectious vaccines without infection. These advances include the use of recombinant DNA technology, peptide synthesis, internal imaging (idiotypic) antibodies, and