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目的评估不同配方益生菌对轻度便秘和相关胃肠道症状的改善作用和对肠道微生态环境及肠道营养吸收的改善效果。方法将126名年龄在25～35岁的志愿者按性别比例随机分为空白对照组、服用丹尼斯克Bi-07双歧杆菌粉剂组和服用丹尼斯克Lpc-37干酪乳杆菌粉剂组。实验组每人每天分别于早上10点及下午4点用温水混合服用2.5 g粉剂,持续服用8周。结果丹尼斯克Bi-07双歧杆菌和丹尼斯克Lpc-37干酪乳杆菌可明显改善肠道微生态环境,促进肠道短链脂肪酸的生成;改善肠道症状,促进肠道通畅,有助于消化吸收。结论丹尼斯克Bi-07双歧杆菌和丹尼斯克Lpc-37干酪乳杆菌对促进人体肠道消化吸收及通畅,肠道微生态环境的改善以及对肠道短链脂肪酸的改善均具有显著的效果。
Objective To evaluate the effects of different formula probiotics on the improvement of mild constipation and related gastrointestinal symptoms and the improvement of gut microflora and intestinal nutrition absorption. Methods A total of 126 volunteers aged 25-35 years old were randomly divided into blank control group, Danisco BS-07 Bifidobacterium powder group and Danisco Lpc-37 Lactobacillus casei powder group. The experimental group was given 2.5 g of powder daily with warm water at 10 a.m. and 4 p.m. daily for 8 weeks. Results Danisco’s Bifidobacterium Bi-07 and Lncock Lpc-37 Lactobacillus casei can significantly improve the intestinal microflora, promote the formation of short-chain fatty acids in the intestine, improve intestinal symptoms, promote intestinal tract patency, and help digestion absorb. Conclusion Danisco’s Bifidobacterium bifidum and Danisco’s Lpc-37 Lactobacillus casei have significant effects on improving intestinal digestion and absorption, improving intestinal microflora, and improving intestinal short-chain fatty acids.