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目的 观察生长抑素联合红霉素对腹部损伤术后肠蠕动功能以及血清炎症因子表达的影响.方法 采用回顾性分析方法选择2015～2016年手术治疗的腹部损伤患者80例,根据术后治疗方法不同将患者平均分为两组,观察组40例患者采用生长抑素(静脉泵注,250μg/h)联合红霉素(静脉滴注,0.9～1.2 g/d)治疗,对照组40例患者采用单独红霉素治疗,两组均持续治疗14天.对比两组患者治疗前后的肠蠕动功能、血清炎症因子水平和术后并发症发生情况.结果 观察组术后肠鸣音恢复时间、肛门排气时间、排便时间以及腹胀持续时间均明显短于对照组,差异有显著性(P<0.05),观察组术后第7天血清白介素-6(IL-6)、白介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)水平均明显低于对照组以及手术前,差异有显著性(P<0.05).观察组术后腹腔感染2例、肠麻痹1例,并发症发生率为7.5％;对照组术后腹腔感染4例、肠麻痹2例,并发症发生率为15.0％.观察组术后并发症发生率明显低于对照组(P<0.05).结论 生长抑素联合红霉素可以有效改善腹部损伤患者的术后胃肠功能恢复情况,同时还可以抑制血清炎性因子的表达,具有良好的临床效果.“,”Objective To observe the efficacy of somatostatin joint erythromycin for improvement of intestinal peristalsis after surgery for abdominal injury,and serum levels of inflammatory cytokines. Methods By using retrospective analysis method to choose 80 patients with surgi-cal treatment for abdominal injury in 2015 to 2016,and they could be divided into two groups according to different postoperative treatment meth-ods,40 patients in observation group were treated with somatostatin (by intravenous injection pump,250 μg/ h)joint erythromycin (by intrave-nous drip,0. 9 to 1. 2 g per day),40 patients in control group treated with erythromycin for 14 days,and patients in these 2 groups were compared with intestinal peristalsis function and serum levels of inflammatory factors before and after the treatment. Results The duration for recovery of bowel sound,anus exhaust time,defecation time and duration for abdominal distention in observation group were significantly shorter than those of control group,and the serum levels of interleukin 6 (IL - 6),interleukin 8 (IL - 8)and tumor necrosis factor α (TNF - α)in observation group in 7 days after operation were significantly lower than those of control group and observation group before the operation. Two cases in observation group had abdominal infection and 1 cases with intestinal paralysis,and its complication rate was 7. 5％ . There were 4 cases in control group had abdominal infection and 2 cases with intestinal paralysis,and the incidence of complications was 15％ . The incidence of postoperative complica-tions in observation group was significantly lower than that of control group (P < 0. 05). Conclusion Somatostatin combined erythromycin can improve the recovery of postoperative gastrointestinal function of patients with abdominal injury,and the combination of these 2 drugs have good clinical effect on suppression of serum expression levels of inflammatorry factors.