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目的探讨输卵管结扎时间对卵巢癌的影响。方法选取2010年4月至2014年4月间收治的90例卵巢癌患者作为试验组,并选取同期收治的135例子宫良性肿瘤、盆底疾病行子宫切除患者作为对照组。比较两组患者输卵管结扎及其结扎不同时间段内患者所占比例。结果试验组患者输卵管结扎率显著低于对照组,未结扎率显著高于对照组,组间差异均有统计学意义P<0.05)。试验组患者结扎时间<5年、5~10年、>10年所占比例与对照组比较,差异无统计学意义(P>0.05)。浆液性癌患者结扎年时间<5年、5~10年、>10年所占比例与黏液性癌比较,差异无统计学意义(P>0.05)。结论输卵管结扎可减少卵巢癌的发生率,但卵管结扎时间对卵巢癌发生无明显影响,因而输卵管结扎可以作为一种对卵巢癌的预防措施加以推广。
Objective To investigate the effect of tubal ligation on ovarian cancer. Methods Ninety ovarian cancer patients who were treated between April 2010 and April 2014 were selected as the experimental group and 135 cases of uterine benign tumor treated by pelvic floor disease were selected as the control group. Patients in both groups were compared with tubal ligation and the proportion of patients in different periods of ligation. Results The tubal ligation rate of the experimental group was significantly lower than that of the control group, the un-ligation rate was significantly higher than that of the control group, the difference was statistically significant (P <0.05). There was no significant difference between the two groups in the ligation time <5 years, 5 ~ 10 years,> 10 years in the experimental group as compared with the control group (P> 0.05). Serous cancer patients with ligation years <5 years, 5 to 10 years,> 10 years, the proportion of mucinous carcinoma compared with the difference was not statistically significant (P> 0.05). Conclusions Tubal ligation can reduce the incidence of ovarian cancer, but the ligation time of oviduct has no obvious effect on the occurrence of ovarian cancer. Tubal ligation can be used as a precautionary measure to ovarian cancer.