本文报告一例罕见的乳房炎性转移癌。女性,62岁,因左前臂出现炎性斑块、水肿和瘙痒4个月而就诊。发病后1月左乳房有小结节,迅速生长最后破溃。体检:左乳房外上象限有2×2cm 溃疡其上有2×2mm 丘疹。溃疡下面硬块累及整个左乳房,其上皮肤呈橘皮样。右侧乳房未扪及肿块。左臂明显水肿,比右臂粗1.5倍。左前臂远端2/3有边界明显的炎性斑块。腋、锁骨上、颈、滑车淋巴结未见肿大。左前臂皮损活检组织象示角化过度。真皮血管周围轻度淋巴细胞浸润。真皮中、上部淋巴管内充满了大的细胞,核染色深,可见不典型有丝分裂。此种细胞与乳房标本组织象看到的恶性细胞相同。诊断为乳房转移到前臂的炎性转移癌。左乳房的左上象限皮肤增厚处摄乳房平片显示 This article reports a rare case of inflammatory metastatic breast cancer. Female, 62 years old, presented with inflammatory plaque, edema and itching in the left forearm for 4 months. After the onset of the disease, there was a small nodule in the left breast in January, and the rapid growth eventually collapsed. Physical examination: The outer quadrant of the left breast has 2 x 2 cm ulcers with 2 x 2 mm papules. The lump under the ulcer affects the entire left breast, and the upper skin is orange peel-like. The right breast has no palpable mass. The left arm was markedly edematous, 1.5 times thicker than the right arm. The distal 2/3 of the left forearm has borderline inflammatory plaques. No enlargement of the lymph nodes was observed in the sacrum, supraclavicular, neck, and trochlear. Left forearm lesion biopsy tissue showed hyperkeratosis. Mild lymphocytic infiltrates around the dermal blood vessels. The middle and upper lymphatic vessels of the dermis are filled with large cells with deep nuclear staining, showing atypical mitoses. Such cells are the same as the malignant cells seen in the mammary tissue. Diagnosed as an inflammatory metastatic carcinoma with breast metastasis to the forearm. Left upper quadrant skin thickening at the breast photo