据报道,近50年来男性精液质量持续下降,不育症的发病率越来越高,有10%的育龄夫妇患有不孕症,其中约50%是丈夫精液质量下降引起~([1])。精液常规质量分析虽是男性生育能力的主要评估指标,但它在全面评价精子的受精能力等方面有一定局限性。近年来临床研究表明:在特发性不育中,有近20%的患 It is reported that in the past 50 years, the quality of men’s semen continued to decline, the incidence of infertility is getting higher and higher, with 10% of couples of childbearing age suffering from infertility, of which about 50% is caused by the decline of her husband’s sperm quality ~ ([1] ). Although routine sperm quality analysis is the main evaluation index of male fertility, it has some limitations in comprehensive evaluation of sperm fertilization ability. In recent years, clinical studies have shown that: in idiopathic infertility, there are nearly 20% of patients