论文部分内容阅读
目的采用脑脊液置换疗法联合尼莫地平治疗蛛网膜下腔出血并观察其疗效。方法将58例蛛网膜下腔出血患者随机分为治疗组和对照组。治疗组30例采用脑脊液置换疗法联合尼莫地平治疗,对照组28例应用尼莫地平治疗,不采用脑脊液置换疗法。两组其它内科治疗按常规进行。结果第28d时进行疗效评估。治疗组治愈26例(86.7%),好转2例,无效2例,总有效率93.3%。脑血管痉挛缓解率100%;对照组治愈13例(46.4%),好转10例,无效5例,总有效率82.1%。脑血管痉挛缓解率75.8%。两组治愈率、总有效率、脑血管痉挛缓解率经统计学处理有统计学意义(P<0.05)。结论脑脊液置换疗法联合尼莫地平治疗蛛网膜下腔出血能防止脑血管痉挛,降低病死率,临床疗效比较满意。
Objective To investigate the efficacy of cerebrospinal fluid replacement combined with nimodipine in the treatment of subarachnoid hemorrhage. Methods 58 cases of subarachnoid hemorrhage were randomly divided into treatment group and control group. Thirty patients in the treatment group were treated with cerebrospinal fluid replacement therapy combined with nimodipine, and 28 in the control group were treated with nimodipine without cerebrospinal fluid replacement therapy. Two other medical treatments were routinely performed. Results The efficacy evaluation was performed on the 28th day. The treatment group cured 26 cases (86.7%), improved in 2 cases, 2 cases, the total effective rate 93.3%. Cerebral vasospasm remission rate was 100%. The control group was cured in 13 cases (46.4%), improved in 10 cases, ineffective in 5 cases, the total effective rate was 82.1%. Cerebral vasospasm remission rate of 75.8%. The two groups of cure rate, total effective rate, cerebral vasospasm remission rate was statistically significant (P <0.05). Conclusion Cerebrospinal fluid replacement therapy combined with nimodipine in the treatment of subarachnoid hemorrhage can prevent cerebral vasospasm and reduce the mortality, and the clinical curative effect is satisfactory.