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目的讨论和分析血清胱抑素C检测对于糖尿病肾功能损伤早期诊断的价值和意义。方法选取2015年9月-2016年6月我院收治的35例糖尿病患者作为研究组,再选取同时期在我院体检的35例正常人为对照组。两组成员均进行血清胱抑素C检测,比较两组的血清胱抑素C水平差异。结果研究组的血清胱抑素C水平明显高于对照组,差异有统计学意义(P<0.05);研究组和对照组的血肌酐及血尿素氮指标比较不存在统计学意义(P>0.05);研究组血清胱抑素C异常检出率显著高于血肌酐和血尿素氮的检出率,差异非常显著(P<0.05)。结论血清胱抑素C检测对于糖尿病肾功能损伤早期诊断有积极意义,能够准确反映出肾功能的损害程度,对早期诊断治疗有很大的帮助。
Objective To discuss and analyze the value and significance of serum cystatin C in the early diagnosis of diabetic renal dysfunction. Methods From September 2015 to June 2016, 35 cases of diabetic patients admitted to our hospital were selected as the research group, and 35 normal persons who were examined in our hospital at the same period were selected as the control group. Serum levels of cystatin C were measured in both groups, and the differences in serum cystatin C between the two groups were compared. Results The level of serum cystatin C in the study group was significantly higher than that in the control group (P <0.05). There was no significant difference in serum creatinine and blood urea nitrogen between the study group and the control group (P> 0.05 ). The detection rate of abnormal cystatin C in study group was significantly higher than that of serum creatinine and blood urea nitrogen (P <0.05). Conclusion Serum Cystatin C has positive significance for the early diagnosis of diabetic renal damage, which can accurately reflect the degree of renal damage and is of great help to the early diagnosis and treatment.