结肠黑变病是一种少见的疾病,1847年 Vir-chow 称此病为结肠黑变病,1958年 Wittocsch 对此病作了比较完整的介绍。1983年 Morgenstern在切除的结直肠肿瘤标本中,研究了结肠肿瘤与黑变病的关系。我院今年在行纤维结肠镜检查的300余例中发现结肠黑变病3例,现报道如下:[例1] 男性,76岁。近一年来大便干,排便困难,一直服用酚酞50～100mg,一日一次,服后 Colon melanosis is a rare disease. In 1847 Vir-chow called this disease colon melanosis. In 1958 Wittocsch made a complete introduction to the disease. In 1983, Morgenstern studied the relationship between colon cancer and melanosis in resected colorectal tumor specimens. In our hospital this year, more than 300 cases of colon colonoscopy were found to have melanosis in 3 cases, and are reported as follows: [Example 1] Male, 76 years old. In the past year, dry stools have caused difficulty in defecation and have been taking phenolphthalein 50-100mg once a day after serving.