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应用蚕豆根尖微核技术研究了林州市饮用水的诱变效应与食管癌发病率和死亡率之间的关系。结果表明 :该市饮用水中存在染色畸变的物质 ,这类物质在各种类型的水样中诱发的蚕豆根尖细胞微核效应与当地居民食管癌发病关系一致。提示 :这些化学诱变剂的存在可能是导致食管癌高发的重要因素之一 ,从而为林州市食管癌水土病因理论提供实验佐证
The relationship between the mutagenic effects of drinking water and the incidence and mortality of esophageal cancer in Linzhou City was studied using the micronucleus technique of Vicia faba root tip. The results showed that there were substances with dye distortion in the drinking water of the city. The micronucleus effect of root tip cells of Vicia faba induced in various types of water samples was consistent with the incidence of esophageal cancer in local residents. It is suggested that the existence of these chemical mutagens may be one of the important factors leading to the high incidence of esophageal cancer, thus providing experimental evidence for the etiology of water and soil causes of esophageal cancer in Linzhou City.