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[目的]对2014~2015年度乌鲁木齐市上消化道癌高危人群进行筛查,探讨筛查的依从性、内窥镜和病理活检对上消化道疾病的检出率,以及上消化道癌和癌前病变的早诊率。[方法 ]在40~69岁乌鲁木齐市居民中,采用问卷调查法筛查出上消化道癌高危人群;经知情同意后,进行内窥镜检查并取活检,对检查结果进行分析。[结果]问卷调查共筛查出上消化道癌高危人群9978人,实际完成筛查1548例,依从性为15.5%;其中,女性依从性(16.4%)高于男性(14.5%),60~69岁年龄组的依从性最高(17.0%),差异有统计学意义(P<0.05)。内窥镜检出胃部病变338例(21.8%),食管病变106例(6.8%)。病理检出胃部病变655例(42.3%),食管病变60例(3.9%)。上消化道癌及癌前病变检出率为0.26%,早诊率为25%;其中胃癌及癌前病变检出1例,食管癌及癌前病变检出3例。[结论]以问卷调查为基础,结合内窥镜及病理检查,能提高早期发现、早期诊断和早期治疗的比例,降低上消化道癌发病率和死亡率,从而提高患者生活质量,减轻个人和社会经济负担。
[Objective] To screen the high risk population of upper gastrointestinal cancer in Urumqi from 2014 to 2015 to investigate the compliance of screening, the detection rate of upper gastrointestinal diseases by endoscopy and pathological biopsy, and the diagnosis of upper gastrointestinal cancer and cancer The rate of pre-lesion diagnosis. [Methods] Among the residents aged 40 ~ 69 in Urumchi, the high risk population of upper gastrointestinal cancer was screened by questionnaire method. After informed consent, endoscopy and biopsy were performed to analyze the examination results. [Results] A total of 9978 people were screened at the high risk of upper gastrointestinal cancer in the questionnaire survey, 1548 cases were actually screened, and the compliance was 15.5%. Among them, the compliance rate of women was higher than that of male (14.4%), The 69-year-old group had the highest compliance (17.0%), the difference was statistically significant (P <0.05). Endoscopy detected gastric lesions in 338 cases (21.8%), esophageal lesions in 106 cases (6.8%). Pathological findings of gastric lesions in 655 cases (42.3%), esophageal lesions in 60 cases (3.9%). Upper gastrointestinal cancer and precancerous lesions detection rate was 0.26%, the diagnosis rate was 25%; gastric cancer and precancerous lesions were detected in 1 case, esophageal cancer and precancerous lesions were detected in 3 cases. [Conclusions] Based on the questionnaire, combined with endoscopy and pathological examination, the proportion of early detection, early diagnosis and early treatment can be increased, the morbidity and mortality of upper gastrointestinal cancer can be reduced, thereby improving patients’ quality of life and alleviating personal and Socio-economic burden.