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35例早产儿应用静脉丙种球蛋白(IVIG).并以未应用IVIG的3O例早产儿和20例正常足月新生儿为对照,同时进行血清lgA、lgG和IgM检测及外周血T淋巴细胞亚群计数。结果表明,早产儿血清lgG水平较足月新生儿低,静注IVIG可以增加早产儿血清IgG.对早产儿感染起预防和治疗作用。早产儿CD4细胞减少,应用IVIG未见免疫抑制现象,而可提高CD4细胞数和CD4/CD8比值,增强抗病能力。
35 preterm infants with intravenous gamma globulin (IVIG). In addition, 30 cases of preterm infants without IVIG and 20 normal term newborns were used as controls. Serum lgA, lgG and IgM levels and counts of T lymphocyte subsets in peripheral blood were also measured. The results showed that preterm serum lgG levels lower than full-term newborns, intravenous IVIG can increase serum IgG in preterm children. Preterm infant infection prevention and treatment. Premature children with CD4 cells decreased, the application of IVIG no immunosuppression, but can increase the number of CD4 cells and CD4 / CD8 ratio, enhance disease resistance.