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目的 :探讨蝎毒复合胶囊 (capsulesofantineoplasticfactorofscorpionvenom ,CAFSV)配合放疗治疗中晚期恶性肿瘤患者的疗效。方法 :84例同期中晚期恶性肿瘤患者 ,随机分为 2组 ,治疗组 41例 ,对照组 43例。治疗组采用CAFSV口服 ,3次 /d ,2粒 /次 ,连续用药 7周 ,配合常规放疗 ;对照组单纯放疗。观察 2组患者在治疗前后的生存质量、T细胞亚群的变化及肿瘤退缩情况。结果 :治疗组的生存质量卡氏评分、免疫功能提高 ,肿瘤明显缩小 ,与对照组比较 ,差异有显著性 (P <0 .0 5 )。结论 :CAFSV具有抑制肿瘤生长 ,提高放疗疗效作用
Objective: To investigate the efficacy of capsules of antagony factorofscorpionvenom (CAFSV) combined with radiotherapy in the treatment of patients with advanced malignant tumors. Methods: Eighty-four patients with advanced malignant tumors were randomly divided into 2 groups, 41 in the treatment group and 43 in the control group. The treatment group was given CAFSV orally 3 times daily for 2 weeks, followed by continuous administration for 7 weeks with conventional radiotherapy, and the control group was treated with radiotherapy alone. Observed the quality of life of patients in the two groups before and after treatment, changes in T cell subsets and tumor shrinkage. RESULTS: The quality of life of the treated group was improved with the Kappes scale, the immune function was improved, and the tumor was significantly reduced. Compared with the control group, the difference was significant (P < 0.05). Conclusion : CAFSV can inhibit tumor growth and improve the efficacy of radiotherapy