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最近的研究表明,红霉素对胃肠运动有类似胃肠多肽蠕动素的作用,可能是由于红霉素与蠕动素受体结合,从而起到蠕动素兴奋剂的作用。因而推测对胃肠运动功能失调有效。为此作者选择10例重症糖尿病性胃轻瘫患者进行研究,以确定红霉素对胃排空的作用。男性3例,女性7例,平均年龄51岁。病人有胰岛素依赖性糖尿病5~41年,既往闪烁扫描均有胃内液体或固体食物排空延长,4例病人有梗阻症状,8例有外周神经疾患,9
Recent studies have shown that erythromycin gastrointestinal motility similar gastrointestinal polypeptide motilin, may be due to erythromycin and motilin receptor binding, which play a role in stimulant. Thus speculated that gastrointestinal motility disorders. To this end the author chose 10 patients with severe diabetic gastroparesis in order to determine the role of erythromycin on gastric emptying. 3 males and 7 females, with an average age of 51 years. Patients with insulin-dependent diabetes 5 to 41 years, previous scintigraphy with gastric fluid or solid food emptying prolonged, 4 patients with obstructive symptoms, peripheral neuropathy in 8 cases, 9