[目的]探讨对慢性肾衰竭维持性血液透析(MHD)病人进行健康指导的方法及效果.[方法]对122例病人血液透析(HD)前、中、后实施健康指导和心理支持,并用自行设计的调查表对研究对象进行评估.[结果]病人疾病保健知识、疾病自我管理能力以及病人接受治疗护理的顺应性在健康指导后明显增强(P“,”Objective: To probe into methods and effect of health guidance for chronic renal failure patients undergoing maintenance hemodialysis (HMD). Method: A total of 122 patients undergoing HMD were offered health guidance and mental support before, during and after hemodialysis respectively. And all cases were evaluated and comparatively analyzed with self-designed questionnaires. Result: The knowledge of health care and illness self-management ability of patients, and the compliance of patients toward accepting treatment and nursing were greatly enhanced after the health guidance (P<0.05). Conclusion: It is feasible to carry out corresponding health guidance and psychological support for MHD patients. However, one should pay attention to the influence of difference of pathogenesis, gender, age and education background of different individuals.