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目的研究短暂性脑缺血发作(TIA)与颈动脉粥样硬化(CAS)斑块的关系,寻找TIA的危险因素。方法应用彩色多普勒对90例TIA患者(病例组)和70例对照患者(对照组)进行检测,比较两组颈动脉粥样硬化斑块和血管狭窄的发生率,观察CAS程度,同时检查胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)、纤维蛋白原(FBG)、空腹血糖(FPG等指标,以研究上述因素之间及其与TIA之间的相关性。结果 TIA组颈动脉中、重度狭窄发生率、颈动脉粥样硬化斑块的发生率、粥样硬化斑块软斑的比率均较对照组高;TIA组IMT较对照组明显增厚;TCH、TG、FIB的值均较对照组明显增高(均P<0.05)。颈动脉粥样硬化斑块是TIA患者的独立危险因素。结论颈动脉粥样硬化斑块与TIA患者密切相关。
Objective To investigate the relationship between transient ischemic attack (TIA) and carotid atherosclerosis (CAS) plaque and to find the risk factors for TIA. Methods Ninety TIA patients (case group) and 70 control patients (control group) were examined by color Doppler imaging. The incidence of carotid atherosclerosis plaque and vascular stenosis in both groups were compared. The degree of CAS was observed. At the same time, Cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL-C), high density lipoprotein (HDL-C), fibrinogen (FBG), fasting blood glucose (FPG and other indicators to study the above factors And the correlation between TIA and TIA.Results The incidence of moderate to severe carotid stenosis, carotid atherosclerosis plaque, and atherosclerotic plaque in TIA group were higher than those in control group. The IMT in TIA group was significantly thicker than that in control group, the values of TCH, TG and FIB were significantly higher than those in control group (all P <0.05) .Atherosclerosis plaque was an independent risk factor for TIA.Conclusion Carotid artery atherosclerosis Sclerosis and TIA patients are closely related.