氯丙嗪用于治疗精神病时剂量较大 ,长期服用 ,易产生一系列毒性作用。作者就大量服用氯丙嗪应注意的问题作一浅述。1　锥体外系反应是长期应用氯丙嗪最常见的不良反应　表现有 :(1 )帕金森综合症。 (2 )静坐不能。(3)急性肌张力障碍 ,多见于用药后的第 1～ 5d。以上三类症状是 Chlorpromazine for the treatment of psychiatric dose, long-term use, easy to produce a series of toxic effects. The author should pay attention to taking chlorpromazine in large quantities to make a brief comment. 1 extrapyramidal reaction is the most common long-term use of chlorpromazine adverse reactions are: (1) Parkinson’s syndrome. (2) can not sit. (3) acute dystonia, more common in the first 1 ~ 5d after treatment. The above three types of symptoms are