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已知胃泌素作为一种标记物,可用于监测胃癌病人,但胃泌素在肺癌、食管癌病人是否有类似作用,目前尚无报道。作者运用放射免疫法检测了52例正常人,动态测定了25例肺癌、22例食管癌和20例非癌胸疾病人手术前、后血清胃泌素水平的变化情况,现将结果及意义报告如下: 本组非癌脚疾病人术前,术后1、7和14天间,血清胃泌素无明显变化(p>0.05)。肺癌、食管癌病人术后7天起血清胃泌素逐渐降低,术后14天可达到或接近正常。肺小细胞癌血清胃泌素平均值>腺癌>鳞癌,依次分别为414.07、119.52、64.43ng/L。胃泌素值与
Gastrin is known as a marker and can be used to monitor patients with gastric cancer. However, whether gastrin has similar effects in patients with lung cancer or esophageal cancer has not yet been reported. The authors detected 52 cases of normal people by radioimmunoassay and dynamically measured changes in serum gastrin levels before and after surgery in 25 cases of lung cancer, 22 cases of esophageal cancer, and 20 cases of non-cancerous breast disease. The results and significance are reported. As follows: Before this group of patients with non-cancerous foot disease, there was no significant change in serum gastrin between days 1, 7 and 14 (p>0.05). Serum gastrin gradually decreased from 7 days after operation in patients with lung cancer and esophageal cancer, and reached or nearly normal 14 days after operation. The mean of serum gastrin in small cell lung cancer> adenocarcinoma> squamous cell carcinoma was 414.07, 119.52, and 64.43 ng/L, respectively. Gastrin and