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目的探讨不同联合用药方式对老年高血压患者的降压效果。方法将2010年1月-2011年6月间在我院住院的老年高血压患者316人随机分为A、B两组，每组158人，A组患者降压方案为每日口服贝纳普利和氯氨地平，B组患者降压方案为每日口服贝纳普利和硝苯地平，连续服用8周，期间每天监测患者的收缩压降压幅度、舒张压降压幅度以判断临床疗效。组间数据利用SPSS13.0进行统计学分析。结果8周治疗结束后A、B两组舒张压的平均降压幅度为14.9mmHg和12.7mmHg，收缩压的降压幅度是32.9mmHg和29.7mmHg，统计学分析不具有显著差异（P=0.069>0.05）。治疗效果为显效、有效、无效及总有效的病例在A组中的比率分别为60.8%、291%、3.8%及96.2%，在B组中的比率分别为47.4%、44.9%、7.6%及92.4%。两组患者治疗总有效率的差异不具有统计学意义（P>0.05），但显效率的差异具有统计学意义（P<0.01）。结论氯氨地平和硝苯地平与贝纳普利的联用治疗高血压患者均具有较好疗效，但氯氨地平与贝纳普利的联用可显著提高患者的治疗效果。“,” Objective To investigate the antihypertensive effect of the combined medication in the treatment of the elderly patients with essential hypertension. Methods 316 elderly patients with hypertension were randomly divided into two groups of which group A was treated with Benazepril and Amiodipine Besylate,group B were treated with Benazepril and nifedipine. 8 weeks later, the systolic blood pressure and the diastolic blood pressure were detected and the reduced pressure amplitude were used to identify the treatment outcome. Al the data were analyzed by SPSS13.0. Results The mean reduced diastolic pressure amplitude in group A and B were 14.9mmHg and 12.7 mmHg , the mean reduced systolic pressure amplitude in group A and B were 32.9 mmHg and 29.7mmHg, which has no significantly difference between the two groups. The frequency of significant effective ,effective, invalid ,total effective cases is 60.8%、291%、3.8%、96.2% in group A, and 47.4%、44.9%、7.6%、92.4% in group B. The total effective frequency between the two groups is similar, while the significantly effective frequency between the two groups is statistical y different (P<0.01).Conclusion Both of the two CCB antihypertensive medicine is good when they are combined with Benazepril ,and the Amiodipine Besylate is better for the patients.