益生菌目前最常应用于消化系统疾病的治疗,如炎症性肠病、抗生素相关性腹泻、新生儿黄疸等。但“卫生假说”的提出及后来越来越多的研究证明肠道微生物能影响人体免疫功能,使益生菌是否能应用于变应性疾病的治疗成为一个热点。1变应性疾病的机制概述变应性疾病包括变应性鼻炎(allergic rhinitis,AR)、哮喘、变应性皮炎、食物过敏等疾病,其发病率目前在全世界范围内日益升高,由AR发展为哮 Probiotics are currently most commonly used in the treatment of digestive diseases, such as inflammatory bowel disease, antibiotic-associated diarrhea, and neonatal jaundice. However, “health hypothesis” and later more and more studies have shown that intestinal microbes can affect the body’s immune function, so that probiotics can be applied to the treatment of allergic diseases has become a hot spot. 1 Overview of the mechanism of allergic diseases Allergic diseases include allergic rhinitis (AR), asthma, allergic dermatitis, food allergies and other diseases, the incidence is currently around the world increasing from AR develops into asthma