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在胰岛素依赖性糖尿病(IDD)的自然病历中,通常胰岛β细胞的自体免疫破坏过程超过数年,才会出现临床症状。尽管胰岛素的纯化获得进展,但IDD的预后在近10～20年内不可能获得明显改善。每4名患者中有3名将发生明显的并发症。IDD的发病率及
In natural history of insulin-dependent diabetes mellitus (IDD), clinical symptoms usually occur when autoimmune destruction of islet beta cells occurs for more than a few years. Despite advances in the purification of insulin, the prognosis of IDD is unlikely to be significantly improved in the next 10 to 20 years. Three out of four patients develop significant complications. The incidence of IDD and