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目的用HRT探讨屈光度、年龄、视盘面积对生理性大视杯各视盘参数的影响。方法用Heidelberg视网膜断层扫描仪对100例生理性大视杯的200只眼的视乳头进行断层扫描获得视乳头结构参数:视盘面积(DA)、视杯面积(CA)、杯盘面积比(CDR)、盘沿面积(RA)、视杯容积(CV)、盘沿容积(RV)、平均视杯深度(MeCD)、最大视杯深度(MxCD)、杯形测量(CSM)、轮廓线高度变化(HVC)、平均视网膜神经纤维层厚度(mRNFLt)、视网膜神经纤维层横截面积(RNFLcsa)、标准参考平面高度(RH)等。随访至少1年以上,用多元线性回归分析方法分析屈光度、年龄、视盘面积对各项视盘参数的影响。结果生理性大视杯视乳头的RA、RV、mRNFLt、RNFLcsa与近视呈正相关,CA、CDR与近视呈负相关(P<0.01)。RA、RV与年龄呈正相关(P<0.01),CA(P<0.01),CDR、CV与年龄呈负相关(P<0.05)。DA大者,CA、CDR、RA、CV、RV相应也大,mRNFLt减小(P<0.01)。结论用HRT获得的生理性大视杯的视乳头结构参数有其特点,CA、CDR、CV与近视、年龄呈负相关、RA、RV与年龄呈正相关。MeCD、MxCD不受屈光度、年龄及视盘面积的影响。
Objective To investigate the effects of diopter, age and optic disc area on the parameters of each optic disc in physiologic optic cup by HRT. Methods Heidelberg retina tomography was used to scan the optic nerve of 200 eyes of 100 cases of physiological large cup to get the structural parameters of the optic disc: optic disc area (DA), cup area (CA), cup - , RA, CV, RV, MeCD, MxCD, CSM, height of contour line HVC, mRNFLt, RNFLcsa, RH and so on. Follow-up for at least 1 year, using multivariate linear regression analysis of diopter, age, optic disc area on the various parameters of the optic disc. Results There was a positive correlation between RA, RV, mRNFLt, RNFLcsa and myopia in CAI, and negative correlation between CA and CDR and myopia (P <0.01). RA and RV were positively correlated with age (P <0.01), CA (P <0.01), and CDR and CV were negatively correlated with age (P <0.05). DA, CA, CDR, RA, CV, RV were also correspondingly large, and mRNFLt was decreased (P <0.01). Conclusions The optic nerve structural parameters of physiological large cup obtained by HRT have its own characteristics. CA, CDR, CV are negatively correlated with myopia and age, while RA and RV are positively correlated with age. MeCD, MxCD from diopter, age and optic disc area.