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７０年代出现了临床可用的前列腺素,而８０年代末期又拥有了孕酮受体阻滞剂米非司酮，使药物流产成为这一孕期的另一种可供选择的方法。与人工流产术相比，用米非司酮和前列腺素进行药物流产是一种安全、有效的方法，而且副作用小，对一些妇女来说药物流产更能被接受，它提供了
The clinically useful prostaglandins emerged in the 1970s and the progesterone receptor blocker mifepristone in the late 1980s, making medical abortion an alternative method of this pregnancy. Compared with abortion, medical abortion with mifepristone and prostaglandin is a safe and effective method with few side effects and is more acceptable to some women for medical abortion