睾丸恶性肿瘤是泌尿生殖系统中主要恶性肿瘤之一。Ⅰ期精原细胞瘤（ＳＧＣＴ）对放疗敏感，而Ⅱ、Ⅲ（Ⅳ）期精原细胞瘤及非精原细胞（ＮＳＧＣＴ）却常需化疗预防及治疗其全身播散及转移。而肿瘤的耐药性常使常规化疗药物不能有效杀伤恶性肿瘤细胞，从而导致肿瘤的复发。因此 Testicular malignancies are one of the major malignancies in the genito-urinary system. Stage I seminoma (SGCT) is sensitive to radiotherapy, whereas stage II, stage III (IV) seminoma and non-spermatogonia (NSGCT) often require chemotherapy to prevent and treat systemic dissemination and metastasis. The tumor resistance often make conventional chemotherapy drugs can not effectively kill malignant cells, leading to tumor recurrence. therefore