论文部分内容阅读
目的:观察左归丸联合二至丸加减治疗肝肾阴虚型隐匿性肾炎的临床疗效。方法:60例患者随机分为治疗组和对照组,各30例。对照组给予常规西医治疗和予黄葵胶囊治疗;治疗组在对照组基础上加用左归丸联合二至丸加减治疗,每天1剂,1月为1疗程,治疗3疗程。观察整体疗效及治疗前后中医证候积分和实验室检查指标[血肌酐(SCr)、尿素氮(BUN)、肾小球滤过率(GFR)、24h尿蛋白定量、尿红细胞计数]的变化。结果:2组临床疗效、中医证候疗效比较,差异有统计学意义(P<0.05)。2组治疗后SCr、BUN、GFR均有改善,与本组治疗前比较,差异有统计学意义(P<0.05);2组治疗后SCr、BUN、GFR比较,差异有统计学意义(P<0.05)。治疗后2组24 h尿蛋白定量、尿红细胞计数均减少,与本组治疗前比较,差异有统计学意义(P<0.05);2组治疗后24 h尿蛋白定量、尿红细胞计数比较,差异有统计学意义(P<0.05)。结论:左归丸联合二至丸加减治疗肝肾阴虚型隐匿性肾炎的疗效显著,值得推广。
Objective: To observe the curative effect of Zuogui Pill and Erzhi Pill on the treatment of occult nephritis with the syndrome of liver and kidney yin. Methods: Sixty patients were randomly divided into treatment group and control group, 30 cases each. The control group was treated with conventional Western medicine and treated with Huang Kui Capsule. The treatment group was treated with Zuogui Pill and Erzhi Pills in addition to the control group. One dose per day for 1 month was given for 1 course of treatment for 3 courses. To observe the overall effect and changes of TCM syndrome scores and laboratory test indicators [serum creatinine (SCr), blood urea nitrogen (BUN), glomerular filtration rate (GFR), 24h urinary protein, urinary erythrocyte count] before and after treatment. Results: The clinical curative effect and TCM syndrome curative effect of the two groups were statistically significant (P <0.05). The levels of SCr, BUN and GFR in both groups improved after treatment, which were significantly different from those before treatment (P <0.05). There was significant difference in SCr, BUN and GFR between the two groups after treatment (P < 0.05). After 24 hours of treatment, urinary protein and urinary erythrocyte count of two groups decreased, with statistical significance (P <0.05) compared with those before treatment in both groups (P <0.05) There was statistical significance (P <0.05). Conclusion: Zuogui pill combined with Erzhi Pill has significant curative effect on occult nephritis with liver-kidney-yin deficiency and is worth promoting.